Metabolic syndrome is characterized by a combination of risk factors for cardiovascular disease and diabetes that are generally linked to insulin resistance and central obesity. Metabolic syndrome ms refers to the clustering of cardiometabolic risk factors including abdominal obesity, hyperglycaemia, dyslipidaemia and elevated blood pressure that are thought to be linked to insulin resistance. Metabolic syndrome, which is consisted of hypertension, dyslipidemia and impaired glucose tolerance, is one of the most significant lifestylerelated disorders that lead to cardiovascular diseases. Introduction metabolic syndrome mets is a growing problem in the united arab emirates uae. Open access journal translational metabolic syndrome research. Because of the relationship between metabolic syndrome and cardiovascular disease, there is a need to understand the mechanisms of metabolic syndrome. Methods papers these manuscripts describe the development of novel methodologies in the field of metabolic. Edwards school of medicine, marshall university, usa 2. The metabolic syndrome and its components and the longterm. Joint association of obesity and metabolic syndrome with. It is well known that obesityinduced chronic inflammation plays a fundamental role in the pathogenesis of ms. The goal of diagnosing the metabolic syndrome is to identify persons at increased risk of cvd. A search was conducted on pubmed, scopus and ovidsp medline and embase using the term metabolic syndrome, prevalence and the name of each south asian country for studies published on or after the year 2000. This study determined the prevalence of mets in emirati females aged 1725 years and.
Journal of metabolic syndromeomics internationaljournal. The metabolic syndrome and its components and the longterm risk of death in patients with coronary heart disease anil nigam, md, msc, martial g. Mar 11, 2014 metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Cardiovascular disease is the leading cause of morbidity and mortality in the world. The metabolic syndrome, however defined, has a stronger association with incident diabetes than that previously demonstrated for coronary heart disease. A crosssectional study of the prevalence of metabolic. Moreover, the prevalence of overweight and obesity is rapidly increasing in the uae especially among young females. Metabolic syndrome is a name for a group of risk factors that occur together and increase the risk for coronary artery disease. Metabolic syndrome mets and psychological distress are hypothesized to have a bidirectional relationship.
The current study was a populationbased survey of cohort of subjects in the metropolitan city of mumbai. Since cardiovascular heart and blood vessel disease is the leading cause of death for adults in developed countries, many medical studies focus on treating or preventing heart disease and stroke. Metabolic syndrome mets is a cluster of metabolic abnormalities that includes hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia. Metabolic syndrome, lipotoxicity, obesity, type 2 diabetes, hypertriglyceridemia. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2. Aggressive lifestyle modification and possible use of medications to treat the conditions that make up the metabolic syndrome may reduce a persons chances of.
Resistance training or strength training has been shown to offer protection. A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh visweshwar, joseph i. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Metabolic syndrome and pregnancy, its prevalence, obstetrical and newborns complications article pdf available in open journal of obstetrics and gynecology 0511. In addition to cvd and type 2 diabetes, individuals with metabolic syndrome are seem ingly more susceptible to other conditions, including polycystic ovary syndrome, fatty liver, cholesterol gallstones, asthma, dis sleep turbances, and some forms of cancer, such as breast, pancreatic, colorectal, and prostate 5, 6. Journal of metabolic syndrome is one of the journals which publish articles related to type 1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes, cardio vascular research, endocrinology, diabetes therapy, diabetic drugs, and genetics of diabetes etc. Relationship between metabolic syndrome and its components with. The metabolic syndrome ms is a multiplex risk factor for atherosclerotic cardiovascular disease ascvd. South asians are prone to a group of risk factors causing metabolic syndrome. Metabolic syndrome in bangladeshi patients of rheumatoid. A total of 548 subjects, who attended the cardiac evaluation camp, were recruited in the study. Syndrome is a group of cardiometabolic risk factors, which comprise of type 2 diabetes, high fasting plasma glucose, hyperglycemia, hyper triglycerides, low hdl cholesterol and abdominal obesity 21. The metabolic syndrome as a disease because of the generalized lack of knowledge of the pathogenic origin, and the varying degree of association of its different components, acknowledgement of the ms as a distinct pathologic entity has been slow and progressive.
Metabolic syndrome ms is characterised by a constellation of individual risk factors of cardiovascular disease. Profile and factors associated with glycaemic control of patients with type 2 diabetes in greece. Metabolic syndrome journalsomics internationaljournal of. While the benefit of exercise and active lifestyles is well documented for prevention and risk reduction of cardiovascular and stroke outcomes, the detailed regiment and recommendations are less clear. Revisiting the metabolic syndrome the medical journal of. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers may be harmful in. Metabolic syndrome represents a cluster of related metabolic abnormalities, including.
Metabolic syndrome mets, also variously known as syndrome x, insulin resistance, etc. Decoding insulin resistance and metabolic syndrome for. Among many upstream factors that are related to metabolic syndrome, obesity, especially visceral obesity, plays an essential role in its pathogenesis. Reducing metabolic syndrome risk using a personalized. Sustained employee engagement of 50% over the course of 1 year. The journal is committed to the rapid publication of the latest laboratory and clinical findings in the fields of diabetes, metabolic syndrome and obesity research. Pdf metabolic syndrome and pregnancy, its prevalence. Department of pharmacy, padmavathi college of pharmacy, dharamapuri, tamil nadu, india. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers may be harmful in patients with diabetes during covid19 pandemic. The global epidemic of the metabolic syndrome ncbi. Translational metabolic syndrome research journal keai.
Metabolic syndrome mets represents a conglomeration of various metabolic abnormalities, including glucose intolerance, hypertension, increased triglycerides, and decreased highdensity lipoprotein cholesterol hdlc. A class of supplements called polyphenols might be what gives espresso this medical advantage. The metabolic syndrome and its components and the long. The metabolic syndrome, a collection of unhealthy body measurements and abnormal laboratory test results, may identify persons at high risk for developing cardiovascular disease. Obesity is associated closely with the metabolic syndrome ms. Open access journal translational metabolic syndrome. They may appear in their original format and may not be copy edited or formatted in the style guide of this journal. Bourassa, md, annik fortier, msc, marieclaude guertin, phd, and. Our academic editors hope that this new journal will be accessed and referred to easily by everybody at any time. Methodsdata are from 2,984 women and men aged 7079 years participating in the health, aging, and body composition study without mobility limitation at baseline. Debate about the clinical usefulness of metabolic syndrome has been ongoing since it was first described in the late 1980s.
This section concerns all aspects of diabetes and metabolic syndrome including but not limited to. Exploring the mechanisms of white at inflammation and resetting the immunological balance in white at. The association of metabolic syndrome is significantly higher in patients with rheumatoid arthritis as compared to healthy controls. Metabolic syndrome mets is a combination of cardiovascular risk factors such. Because metabolic syndrome crosses paths with obesity, heart disease, and diabetes research, a great many of the papers on metabolic syndrome have been published in highimpact journals from these other fields, such as circulation, diabetes, and the international journal of obesity.
Proponents of the syndrome encourage its use as a clinical tool to help identify people who may be at higher risk of cardiovascular disease and diabetes. Mets is strongly associated with an increased risk of developing atherosclerotic cardiovascular disease cvd. Metabolic syndrome journal articles subclinical hypothyroidism and cardiometabolic biomarkers a new study explores the possible relationship between subclinical hypothyroidism and. Because each component that makes up the versions of the metabolic syndrome increases cvd risk 34, 36, 37, 62, 68, 69, it seems prudent to treat any of these abnormalities that are present. The metabolic complications associated with obesity, suchas insulin resistance, hypertension, hyperlipidemia, and the potential for arteriosclerotic heart disease, are on the rise in the pediatric population. The incorporation of physical activity and exercise represents a clinically important aspect in the management of metabolic syndrome, hypertension, and diabetes.
Furthermore, it would not be too surprising that the more. These findings suggest that screening for metabolic syndrome in patients with ra may reduce the risk of cardiovascular diseases in these patients. Metabolic syndrome was first discussed in classical times, taking form. Pdf access policy full text access is free in html pages. Effects of metabolic syndrome open access journals. The metabolic syndrome is a highly prevalent condition that affects a considerate number of adults and has become increasingly relevant to many disciplines in clinical medicine. Department of biotechnology, villamarie college, hyderabad, india. Insulin resistance, visceral adiposity, atherogenic dyslipidemia. Insulin resistance, visceral adiposity, atherogenic dyslipidemia, endothelial dysfunction, genetic susceptibility, elevated blood pressure, hypercoagulable. South asians are prone to metabolic syndrome, which is characterized by high blood pressure, abdominal obesity, high triglyceride levels, low hdl levels, and high blood glucose levels. Metabolic syndrome markers in wistar rats of different ages. Metabolic syndrome markers in wistar rats of different.
Apr 27, 2012 metabolic syndrome is association clinical signs of diseases that increase the risk of cardiovascular disease, which is the leading cause of death in the world. Journal principles all manuscripts submitted to diabetes and metabolic syndrome. Trends in the prevalence of metabolic syndrome and its. The number of metabolic syndrome components also influences the degree of risk. The prevalence of metabolic syndrome in south asia. Its clinical value for diabetes prediction remains uncertain. Strict glycaemic control early in the treatment process has been shown to reduce the occurrence of micro and macro vascular complications of. However, few studies have evaluated the prevalence of mets among young female adults in the uae.
Obesity is a major risk factor for various metabolic disorders such as type 2 diabetes, nonalcoholic fatty liver disease and atherosclerotic cardiovascular diseases. Orphanet journal of rare diseases inherited metabolic. Recent advances in managingunderstanding the metabolic syndrome. Mar 27, 2015 the objective of this study was to estimate the prevalence of metabolic syndrome and its individual components in south asia region. In one study, the presence of four or more metabolic syndrome risk factors was associated with a 3. All of the 38 unique titles on the journal lists are in the top 50% in their fields in essential science. Obesity, diabetes and metabolic syndrome clinical group. New research finds a relationship between moderate espresso utilization and a decreased danger of creating metabolic disorders.
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