Insulin resistance, visceral adiposity, atherogenic dyslipidemia. All of the 38 unique titles on the journal lists are in the top 50% in their fields in essential science. Mar 27, 2015 the objective of this study was to estimate the prevalence of metabolic syndrome and its individual components in south asia region. Metabolic syndrome mets is a combination of cardiovascular risk factors such. Methodsdata are from 2,984 women and men aged 7079 years participating in the health, aging, and body composition study without mobility limitation at baseline. Relationship between metabolic syndrome and its components with. Bourassa, md, annik fortier, msc, marieclaude guertin, phd, and. The metabolic syndrome and its components and the longterm. Because metabolic syndrome crosses paths with obesity, heart disease, and diabetes research, a great many of the papers on metabolic syndrome have been published in highimpact journals from these other fields, such as circulation, diabetes, and the international journal of obesity. A crosssectional study of the prevalence of metabolic. Introduction metabolic syndrome mets is a growing problem in the united arab emirates uae. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2.
In one study, the presence of four or more metabolic syndrome risk factors was associated with a 3. Recent advances in managingunderstanding the metabolic syndrome. However, few studies have evaluated the prevalence of mets among young female adults in the uae. The journal is committed to the rapid publication of the latest laboratory and clinical findings in the fields of diabetes, metabolic syndrome and obesity research. Mets is strongly associated with an increased risk of developing atherosclerotic cardiovascular disease cvd. A total of 548 subjects, who attended the cardiac evaluation camp, were recruited in the study. Department of pharmacy, padmavathi college of pharmacy, dharamapuri, tamil nadu, india. South asians are prone to a group of risk factors causing metabolic syndrome. Metabolic syndrome journal articles subclinical hypothyroidism and cardiometabolic biomarkers a new study explores the possible relationship between subclinical hypothyroidism and.
New research finds a relationship between moderate espresso utilization and a decreased danger of creating metabolic disorders. Its clinical value for diabetes prediction remains uncertain. The prevalence of metabolic syndrome in south asia. Metabolic syndrome was first discussed in classical times, taking form. These findings suggest that screening for metabolic syndrome in patients with ra may reduce the risk of cardiovascular diseases in these patients. Methods papers these manuscripts describe the development of novel methodologies in the field of metabolic. Obesity is a major risk factor for various metabolic disorders such as type 2 diabetes, nonalcoholic fatty liver disease and atherosclerotic cardiovascular diseases. Our academic editors hope that this new journal will be accessed and referred to easily by everybody at any time. Proponents of the syndrome encourage its use as a clinical tool to help identify people who may be at higher risk of cardiovascular disease and diabetes.
A search was conducted on pubmed, scopus and ovidsp medline and embase using the term metabolic syndrome, prevalence and the name of each south asian country for studies published on or after the year 2000. The number of metabolic syndrome components also influences the degree of risk. Effects of metabolic syndrome open access journals. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers may be harmful in. The global epidemic of the metabolic syndrome ncbi. Moreover, the prevalence of overweight and obesity is rapidly increasing in the uae especially among young females. The metabolic complications associated with obesity, suchas insulin resistance, hypertension, hyperlipidemia, and the potential for arteriosclerotic heart disease, are on the rise in the pediatric population. Insulin resistance, visceral adiposity, atherogenic dyslipidemia, endothelial dysfunction, genetic susceptibility, elevated blood pressure, hypercoagulable.
The metabolic syndrome ms is a multiplex risk factor for atherosclerotic cardiovascular disease ascvd. Backgroundalthough both obesity and the metabolic syndrome mets are known risk factors for decline in physical function, the joint association of obesity and metabolic alterations with risk of incident mobility limitation is unknown. Furthermore, it would not be too surprising that the more. The metabolic syndrome, a collection of unhealthy body measurements and abnormal laboratory test results, may identify persons at high risk for developing cardiovascular disease. Metabolic syndrome markers in wistar rats of different. It is well known that obesityinduced chronic inflammation plays a fundamental role in the pathogenesis of ms.
The metabolic syndrome as a disease because of the generalized lack of knowledge of the pathogenic origin, and the varying degree of association of its different components, acknowledgement of the ms as a distinct pathologic entity has been slow and progressive. The metabolic syndrome is a highly prevalent condition that affects a considerate number of adults and has become increasingly relevant to many disciplines in clinical medicine. Edwards school of medicine, marshall university, usa 2. Journal of metabolic syndrome is one of the journals which publish articles related to type 1 diabetes mellitus, type 2 diabetes mellitus, gestational diabetes, cardio vascular research, endocrinology, diabetes therapy, diabetic drugs, and genetics of diabetes etc. A class of supplements called polyphenols might be what gives espresso this medical advantage. Pdf metabolic syndrome and pregnancy, its prevalence. Sustained employee engagement of 50% over the course of 1 year. The metabolic syndrome and its components and the longterm risk of death in patients with coronary heart disease anil nigam, md, msc, martial g. Metabolic syndrome journalsomics internationaljournal of. Because of the relationship between metabolic syndrome and cardiovascular disease, there is a need to understand the mechanisms of metabolic syndrome. The metabolic syndrome and its components and the long. Metabolic syndrome mets is a cluster of metabolic abnormalities that includes hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia. Because each component that makes up the versions of the metabolic syndrome increases cvd risk 34, 36, 37, 62, 68, 69, it seems prudent to treat any of these abnormalities that are present. Resistance training or strength training has been shown to offer protection.
Obesity, diabetes and metabolic syndrome clinical group. Trends in the prevalence of metabolic syndrome and its. Metabolic syndrome markers in wistar rats of different ages. Aggressive lifestyle modification and possible use of medications to treat the conditions that make up the metabolic syndrome may reduce a persons chances of. South asians are prone to metabolic syndrome, which is characterized by high blood pressure, abdominal obesity, high triglyceride levels, low hdl levels, and high blood glucose levels. Angiotensinconverting enzyme inhibitors and angiotensin receptor blockers may be harmful in patients with diabetes during covid19 pandemic. Metabolic syndrome is a name for a group of risk factors that occur together and increase the risk for coronary artery disease. Joint association of obesity and metabolic syndrome with. Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Metabolic syndrome mets represents a conglomeration of various metabolic abnormalities, including glucose intolerance, hypertension, increased triglycerides, and decreased highdensity lipoprotein cholesterol hdlc. Metabolic syndrome ms is characterised by a constellation of individual risk factors of cardiovascular disease. Mar 11, 2014 metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Open access journal translational metabolic syndrome. Metabolic syndrome is characterized by a combination of risk factors for cardiovascular disease and diabetes that are generally linked to insulin resistance and central obesity.
They may appear in their original format and may not be copy edited or formatted in the style guide of this journal. The incorporation of physical activity and exercise represents a clinically important aspect in the management of metabolic syndrome, hypertension, and diabetes. Debate about the clinical usefulness of metabolic syndrome has been ongoing since it was first described in the late 1980s. Reducing metabolic syndrome risk using a personalized. Journal principles all manuscripts submitted to diabetes and metabolic syndrome. The goal of diagnosing the metabolic syndrome is to identify persons at increased risk of cvd.
Department of biotechnology, villamarie college, hyderabad, india. Pdf access policy full text access is free in html pages. Strict glycaemic control early in the treatment process has been shown to reduce the occurrence of micro and macro vascular complications of. The association of metabolic syndrome is significantly higher in patients with rheumatoid arthritis as compared to healthy controls. Decoding insulin resistance and metabolic syndrome for.
Translational metabolic syndrome research journal keai. Apr 27, 2012 metabolic syndrome is association clinical signs of diseases that increase the risk of cardiovascular disease, which is the leading cause of death in the world. Obesity is associated closely with the metabolic syndrome ms. Metabolic syndrome, lipotoxicity, obesity, type 2 diabetes, hypertriglyceridemia. Orphanet journal of rare diseases inherited metabolic. Profile and factors associated with glycaemic control of patients with type 2 diabetes in greece.
Among many upstream factors that are related to metabolic syndrome, obesity, especially visceral obesity, plays an essential role in its pathogenesis. This section concerns all aspects of diabetes and metabolic syndrome including but not limited to. Metabolic syndrome represents a cluster of related metabolic abnormalities, including. Metabolic syndrome and pregnancy, its prevalence, obstetrical and newborns complications article pdf available in open journal of obstetrics and gynecology 0511. Exploring the mechanisms of white at inflammation and resetting the immunological balance in white at. Since cardiovascular heart and blood vessel disease is the leading cause of death for adults in developed countries, many medical studies focus on treating or preventing heart disease and stroke. Revisiting the metabolic syndrome the medical journal of. A panel for early detection, management, and risk stratification in the west virginian population krithika srikanthan 1, andrew feyh, haresh visweshwar, joseph i. Open access journal translational metabolic syndrome research. Cardiovascular disease is the leading cause of morbidity and mortality in the world. The current study was a populationbased survey of cohort of subjects in the metropolitan city of mumbai.
Metabolic syndrome mets and psychological distress are hypothesized to have a bidirectional relationship. While the benefit of exercise and active lifestyles is well documented for prevention and risk reduction of cardiovascular and stroke outcomes, the detailed regiment and recommendations are less clear. In addition to cvd and type 2 diabetes, individuals with metabolic syndrome are seem ingly more susceptible to other conditions, including polycystic ovary syndrome, fatty liver, cholesterol gallstones, asthma, dis sleep turbances, and some forms of cancer, such as breast, pancreatic, colorectal, and prostate 5, 6. This study determined the prevalence of mets in emirati females aged 1725 years and. White adipose tissue at is the primary site for the initiation and exacerbation of obesityassociated inflammation. Syndrome is a group of cardiometabolic risk factors, which comprise of type 2 diabetes, high fasting plasma glucose, hyperglycemia, hyper triglycerides, low hdl cholesterol and abdominal obesity 21. The metabolic syndrome, however defined, has a stronger association with incident diabetes than that previously demonstrated for coronary heart disease. Metabolic syndrome ms refers to the clustering of cardiometabolic risk factors including abdominal obesity, hyperglycaemia, dyslipidaemia and elevated blood pressure that are thought to be linked to insulin resistance. Journal of metabolic syndromeomics internationaljournal. Metabolic syndrome mets, also variously known as syndrome x, insulin resistance, etc.
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